Plasticity of the Asialoglycoprotein Receptor Deciphered by Ensemble FRET and Single-Molecule Counting PALM
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چکیده
منابع مشابه
Plasticity of the asialoglycoprotein receptor deciphered by ensemble FRET imaging and single-molecule counting PALM
The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Cell Biology and Metabolism Branch 1: Section on Organelle Biology 2: Unit on Cellular Polarity National Institutes of Health, 18 Library Drive, Bethesda, MD 20892, USA 3: Department of Biophysics and Cell Biology, Cell Biology and Signaling Research Group of the Hungarian Academy of Sciences, Medical and Healt...
متن کاملPlasticity of the asialoglycoprotein receptor deciphered by ensemble FRET imaging and single-molecule counting PALM imaging.
The stoichiometry and composition of membrane protein receptors are critical to their function. However, the inability to assess receptor subunit stoichiometry in situ has hampered efforts to relate receptor structures to functional states. Here, we address this problem for the asialoglycoprotein receptor using ensemble FRET imaging, analytical modeling, and single-molecule counting with photoa...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.2354